Welcome to the Help & Information pages of morFeus. Here, you will find information on using the web-server, interpreting the output, as well as on how to download the virtual machine of morFeus for local command-line usage.

morFeus web-server help

Input

RefSeq Protein ID
Enter the Identifier of the query. Only RefSeq Identifiers from the NCBI RefSeq protein database are valid (example: NP_595754).

Database
Chose the database you want to search against. You can chose between all species, eukaryota, fungi/metazoa, viridiplantae or bacteria. All database search options are based on the NCBI RefSeq protein database.

E-mail
You need to enter your e-mail address to get notification and addresses of the finished jobs. Highly recommended, as morFeus jobs can take a long time (several hours).

Search Options

E-value
Chose the E-value cut-off for the BLAST and back-BLAST searches. Depending on your search query, you will chose either a low or high cut-off. For search queries with only remote similarity to orthologs, an initial setting of 100 is recommended.

Low-Complexity Filtering
Turn filtering of low-complexity regions in proteins on or off. Default: on.

Composition-based Statistics
Method to adjust the matrix to compensate for amino acid composition. See more information on composition-based statistics @ the NCBI.